Exosomes

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What it is Exosomes Treatment

Exosomes are the up-to-date solution of regenerative aesthetic medicine against the signs of time. In treating the symptoms of ageing, where the gradual decline of key proteins such as collagen and elastin leads to visible signs of skin ageing, exosomes are emerging as powerful rejuvenating agents.

Treatment Duration	20-30 minutes
Result Appears	8 – 12 months
Cost	Starts at 300€ (session price per package deal)
Technique	Injectable, non-invasive treatment
Doctor’s Specialty	Dermatologist, Plastic Surgeon
Pain Level	Painless
Anaesthesia	Anaesthetic cream
Recovery Time	Zero time is needed

Cosmetic Derma Medicine Facilities

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The specialized medical team, modern medical methods and the modern and luxurious spaces of the clinics offer the ultimate experience of hospitality, service and provision of health and beauty services.

Benefits of treatment

Exosomes are the cutting edge of skin health and beauty treatments, with multiple benefits that are not only limited to anti-aging, but also address scarring, hair loss and other skin problems and conditions.

Reduction of wrinkles and fine lines
Increased skin elasticity
Strengthening skin firmness
Minimize the appearance of pores
Addressing inflammation
Reduction of puffiness and dark circles under the eyes
Even skin tone
Skin glow
Reduced hyperpigmentation
Lifting effect, youthful face
Skin protection from external factors
Overall enhancement of skin’s health

What are the exosomes

Exosomes are extracellular nanocystidia secreted by eukaryotic cells. They contain lipids, proteins, amino acids, enzymes, cytokines, growth factors, and genetic material (DNA, RNA) that regulate cell behaviour.

They play an important role in the mechanism of cellular self-renewal. By moving through blood, lymph and other body fluids, exosomes transmit therapeutic instructions and nutrients from one cell to another, which serve to repair DNA and regenerate neighbouring or distant recipient cells that have been damaged.

How do they work

Delivering a rich supply of growth factors, enzymes and miRNAs, these nanocystidia trigger the cellular processes necessary to maintain youthful skin vitality and resilience, as they play a key role in remodelling the extracellular matrix, increasing angiogenesis and enhancing skin tissue regeneration.

Plant derived exosomes

Plant-derived exosomes have turned a new page in regenerative medicine treatments. They come from various plants such as fruits, vegetables and herbs, selected for their resilience and healing properties.

Their compatibility with the cells of the human body ensures their safety and effectiveness in skin rejuvenation.

Rich in bioactive molecules, including vitamins, antioxidants and growth factors, plant derived exosomes offer a natural and effective treatment in skin care. A host of clinical studies have shown that plant derived exosomes significantly enhance collagen production, improve skin elasticity and mitigate the effects of aging as well as the damage caused by photo-aging.

Exosomes or autologous PRP mesotherapy?

Platelet Rich Plasma (PRP) is a regenerative therapy that utilizes blood growth factors to rejuvenate the skin and has proven high efficacy in reducing wrinkles, increasing skin thickness and accelerating tissue healing.

Although PRP remains a cornerstone of aesthetic medicine, exosome treatment is emerging as an equally effective alternative due to its unparalleled wealth of growth factors and cellular regeneration mechanisms.

While the efficacy of PRP is undeniable, its multitude of growth factors pales in comparison to the vast variety found within exosomes. Exosomes contain over 300 growth factors, making them 100 times more potent than PRP. Clinical studies have demonstrated their ability to stimulate skin cells, increasing elastin production by up to 300% and collagen synthesis by up to 600%.

The steps of the treatment

Cleansing of the treatment area and application of local anaesthetic cream
Treatment starts by applying exosome serum to the skin
Since the treatment is done with microneedling, the depth of action of the needles is adjusted according to the area and the skin problem
Moisturizing cream is applied at the end of the treatment
The doctor gives instructions, such as using sunscreen with a high SPF and avoiding anticoagulant medications
You return home and resume your daily activities as normal

Areas of application

Exosome treatment is applied to the face and body in any areas that need skin regeneration and healing, such as:

Face
Neck
Chest, neckline, décolleté
Hands
Belly
Knees
Thighs
Scalp

The application techniques

Exosomes are applied by mesotherapy microneedling or by topical application

Microneedling

The latest generation microneedling allows through micro-needles the penetration and absorption of exosomes directly into the deeper layers of the skin, thus maximizing their therapeutic effects. By targeted delivery of the bioactive molecules of exosomes, the natural processes of skin regeneration and healing are directly stimulated.

Local application

The local application of exosomes is an easy and quick method that is used mainly on sensitive skin. Through topical application of serum, exosomes penetrate the upper layer of the skin, known as the stratum corneum, channeling their therapeutic load into the epidermis and dermis.

Compared to microneedling, due to limited penetration into the deeper layers of the skin it may require more sessions.

Why choose us

At Cosmetic Derma Medicine we have the most specialized dermatologists and the most renowned specialists in aesthetic applications in Greece and the achievements of our doctors are recognized at an international level. If you are interested in cosmetic medicine treatment, book an appointment at one of our Clinics in Greece and Cyprus, where our experts will inform you about the exosomes and the solutions that best meet your needs.

FAQs

Your doctor will recommend that you do not take certain medicines for 7 to 10 days before treatment, such as anticoagulants, non-steroidal anti-inflammatory drugs (NSAIDs) such as aspirin and ibuprofen, and immunosuppressants, because they affect blood clotting and may increase the risk of bleeding and bruising.

The same is true for some supplements such as vitamins C and E, Omega-3 fatty acids, coenzyme Q10, and some herbs with anti-inflammatory effects such as garlic, ginkgo biloba and turmeric.

It is normal after treatment to experience slight redness and swelling in the area that may last up to 48 hours. Apply cold compresses to reduce swelling and moisturizer 2-3 times a day.

Wash your hands before touching your skin to protect it from any kind of infection. You can clean your face with a mild cleanser 24 hours after treatment.

Avoid direct exposure to the sun for 48 hours and use a sunscreen with a high SPF.

Avoid vigorous activities, such as exercise and sauna, for 24 hours after treatment.

Exosomes are produced by eukaryotic cells, which include stem cells. While exosomes are extracellular nanocystidia, stem cells are harmless cells that have the ability to self-renew and differentiate into various cell types. Both have demonstrated in a plethora of clinical studies high efficacy in tissue regeneration. However, stem cells have raised ethical concerns about creating human embryo models in the laboratory.

Several factors affect the effectiveness of exosome therapy.

The time required for visible results varies depending on the area of application. For example, the face shows faster results compared to other areas.

The severity of the problem also determines the number of sessions required. More severe problems, such as deep scars, usually require more than one session.

Age and skin quality are also important factors, with younger and healthier skin responding more quickly.

In addition, lifestyle affects the results. A healthy diet, exercise, avoiding smoking and getting enough sleep all help to maintain results.

In the majority of cases, the first visible results are seen after 1 – 2 months and the final results after 3 – 4 months, depending on the factors mentioned above.

To maintain the results, it is recommended to repeat the treatment every 6 – 12 months.

Treatment with exosomes is suitable for everyone who is in good health.

You cannot undergo exosome treatment during pregnancy and breastfeeding, although there is no scientific evidence of risk in these situations.

You cannot undergo treatment if you have autoimmune diseases such as multiple sclerosis, systemic lupus erythematosus or rheumatoid arthritis. The treatment is also not indicated in active cancer or some chronic conditions such as cardiovascular problems, HIV/AIDS infections or hepatitis B and C.

Any skin infections such as active herpes and staphylococcus and the possibility of an allergic reaction to a component of the formulation are additional contraindications.

For the safety and effectiveness of treatment, we will consider your medical history, any medications you are taking or allergies you have in order to have a successful treatment.