Facial Mesotherapy

Facial Mesotherapy is commonly known for its effectiveness in skin rejuvenation and it is considered to be one of the most popular treatments of Aesthetic Medicine.

Facial Mesotherapy
Dr. Konstantina Mamali Dermatologist – Venereologist

“Facial Mesotherapy effectively treats skin aging problems and it is suitable for both men and women”, Dr. Konstantina Mamali states. “Exposure to sunlight, fatigue and everyday life stress, leave their mark on the skin. Facial Mesotherapy is the solution to those aging skin marks and helps renew and restore the natural skin radiance and elasticity.”

Dermatologist – Venereologist Dr. Konstantina Mamali

What is it Facial Mesotherapy

Mesotherapy was first developed in 1952 from a French practitioner, called Dr. Michel Pistor, and it is a therapeutic technique of multiple injections, in which little quantities of drugs and other therapeutic agents are injected under the skin. Mesotherapy is one of the most modern and effective treatments, as it targets exactly the part of skin that need to be repaired and it offers a natural result.

The application of Facial Mesotherapy is indicated in cases of dehydration and relaxation of the skin, loss of firmness, as well as after prolonged exposure to the sunlight (skin photoaging).

During Mesotherapy, a small amount of mesotherapy solution is applied on the skin surface, and with injections or with micro needling the solution can reach deeper layers of skin. One of the advantages of Mesotherapy is that it rejuvenates skin with the use of natural ingredients, vitamins and hyaluronic acid, and at the same time the skin itself produces collagen and hyaluronic acid because of the tiny injuries that occur to the skin.

Areas Of Application

According to Dermatologist – Venereologist Dr. Amalia Tsiatoura, both the Mesotherapy with vitamins and/or hyaluronic acid, and the Autologous Mesotherapy can be applied on:

  • Face – Eyes
  • Neck
  • Décolleté
  • Arms

Skin Loose

Skin loosening of the face and neck is an aesthetic problem that afflicts both men and women, at any age. Skin relaxation is mainly caused by the loss of collagen and elastin fibers, substances that are necessary for a firm and youthful skin. Skin relaxation is also caused by other exogenous factors, such as smoking, sunlight, and frequent weight fluctuations. Sometimes, genetic background can lead to skin aging and can start at a young age, even from 25 years. As collagen and elastin fibers decrease, skin relaxation, fine lines and wrinkles appear.

Skin aging is an inevitable process. Aged skin appears to be rough and dehydrated, and wrinkles appear. Although there are several ways to avoid skin aging, such as heathy diet, use of sunscreen, consumption of fruits and vegetables and various cosmetic dermatology treatments, yet aging cannot be prevented, but only delayed. Facial Mesotherapy is the ideal treatment for the aforementioned problems. At the same time, when combined with other treatments performed in Cosmetic Derma Medicine, such as Facial Microdermabrasion, Ultrasound – RF, Hyaluronic Acid and Neurotoxin Treatment, contribute to the treatment of skin relaxation and anti-aging.

Facial mesitherapy treatment.
Facial mesitherapy treatment.

How is it applied

Depending on the application method, Facial Mesotherapy can be either injectable or non-injectable. During injectable mesotherapy, the solution is injected in the selected part of skin with the use of fine lines. In non-injectable mesotherapy no needles are used, and the solution is penetrated into the skin with the help of tiny channels created on the skin surface with a special micro-needling device, also known as Dermapen Mesotherapy.

In Cosmetic Derma Medicine, Facial Mesotherapy can be applied in both ways. Either by injecting the solution under the skin with very thin insulin syringe needles, or by using a special micro needling device called Dermapen, during which the Mesotherapy solutions reach the required depth through the tiny channels.

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Before – After Results

Mesotherapy is used for:

  • Deep hydration
  • Fine wrinkles treatment
  • Prevention of new wrinkle formation
  • Black spots removal
  • Tear trough treatment
  • Brightness and Healthy look of the skin
  • Skin tightening

The results of Facial Mesotherapy are immediately shown, after the very first session, by improving the texture and appearance of the skin. The desired aesthetic result is achieved cumulatively after 4-6 sessions with an interval of 15-20 days. After the first 3 months, it is suggested to repeat the treatment every 2-6 months, depending on the personal needs of each patient.

Facial mesotherapy result before after


  • Vitamins Mesotherapy

    Delivers amino acids, minerals and vitamins directly into the mesodermal layer of the skin

  • Mesotherapy with Hyaluronic Acid

    Apart from vitamins and amino acids, it also contains cross-linked hyaluronic acid, which has the ability to hold 1000 times its weight in water and offers deep moisture.

  • Autologous Facial Mesotherapy

    It owes its effectiveness on the patient’s blood. It is considered to be the highest form of mesotherapy, as the growth factors contained in plasma lead to proliferation of skin fibroblasts and production of new collagen and elastin, leading to skin anti-aging and rejuvenation.

With the Vitamins Mesotherapy skin is enriched with a solution of nutrients rich is vitamins, coenzymes, minerals and amino acids, which contribute to anti-aging. Mesotherapy with Hyaluronic Acid aims to skin hydration and tightening. It also nourishes and repairs damaged skin cells, and restores skin’s youthfulness and firmness.


The epidermal layer is the outer part of the skin and the barrier that separates our body from any harmful substances coming from the environment. It is in direct contact with the external environment and for this reason the skin is extremely vulnerable to many infections. The dermis is the intermediate tissue, which is responsible for the texture, density and thickness of the skin. Beneath, lays the subcutaneous tissue, the fatty tissue that connects the skin to the underlying tissues.

The substances contained in the Facial Mesotherapy solution aim at the regeneration, hydration, tightening and smoothing of the skin. Specifically, the Mesotherapy solution consists of the following substances:

Vitamin C

It offers antioxidant protection. It also promotes melanin production and helps skin hydration.

Vitamin E

Protects the cell membrane and enhances the blood microcirculation of the skin.

Vitamin A

Enhances the proliferation of skin cells and offers anti-aging protection.

Vitamin D

Contributes to calcium synthesis

Vitamin B Complex

They enhance cellular respiration and promote collagen production.

Coenzyme Q10

Contributes to Vitamin E and Vitamin C production, as well as in the regular function of skin cells


Facial Mesotherapy is ideal for both women and men, regardless of age. The effectiveness of the treatment depends mainly on the skin type, and the problem we want to solve. Facial Mesotherapy using the special micro-needling device Dermapen has the following advantages:

  • It is a completely safe treatment
  • It requires no recovery time
  • It can be applied on any part of the skin
  • It encourages natural skin regeneration

The higher level of Mesotherapy

Is the Autologous Mesotherapy

  • 20-30 years old

    For bright skin and prevention of wrinkles formation

  • 30-40 years old

    It soothes fine lines and wrinkles, stimulates skin elasticity, and restores hydration and radiance.

  • 45+ years old

    Correction of signs of aging, reduction of fine lines and wrinkles and restoration of skin hydration and elasticity.


Facial Mesotherapy

What should I expect after the Facial Mesotherapy treatment?

Facial Mesotherapy is a simple, painless, and without side-effects treatment, that allows the patient to return immediately to his/her daily activities. After Facial Mesotherapy the following contraindications may occur, yet they are rare and mild:

  • Temporary erythema and edema in the form of puffiness which subsides within the next few hours.
  • S bruises that go away quickly.

After its completion, special regenerative creams are required to maximize the effect and to offer sun protection.

Are there any contraindications after the Facial Mesotherapy treatment?

In general, there are no serious contraindications associated with facial mesotherapy. However, the treatment should be avoided by people who take anticoagulants, as bruising may occur during treatment.

Also, Facial Mesotherapy is not ideal for people who have severe skin infections, herpes infection or allergies. As a precaution, women who are pregnant should wait until the end of the pregnancy.

Are there any side-effects associated with Facial Mesotherapy treatment?

Facial Mesotherapy is a painless and absolutely safe treatment, provided that it is performed by specialized Doctors – Dermatologists. As the Dermatologist – Venereologist Dr. Konstantina Mamali emphasized, in rare cases mild symptoms have been observed such as:

  • Pain in the area of application
  • Mild swelling that lasts a few hours
  • Sensitivity and redness
  • Eczema (bruises)
  • Itching

How much does Facial Mesotherapy cost?

The cost of facial mesotherapy depends on the type of solution used and the areas of application. The price of facial mesotherapy should not be the only criteria for choosing the right clinic, as the experience of the doctors, the material used, as well as the technique applied are of great importance.

Why should I choose Cosmetic Derma Medicine for Facial Mesotherapy?

Cosmetic Derma Medicine Medical Group is one of the largest and most specialized medical group with more than 15 years of experience in Dermatology & Plastic Surgery. Medical Director of Cosmetic Derma Medicine is the Dermatologist – Venereologist Dr. Amalia Tsiatoura, while the staff consists of a large medical team of extremely experienced and specialized doctors and a fully trained nursing team.

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