Total Plasma Lift

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Total Plasma Lift: the leading anti-aging treatment

What is the treatment? Total Plasma Lift

Reveal your most radiant, smooth and youthful skin with the top anti-aging and bloodless lifting treatment. Cosmetic Derma Medicine is the first clinic to introduce the Total Plasma Lift anti-aging protocol, the combination of two top facial rejuvenation treatments, Fractional Laser CO2 and Autologous Mesotherapy PRP, maximizing the benefits of tightening, reconstruction and tissue repair they achieve.

Treatment Duration 30 – 45 minutes
Result Appears Right after treatment – Final results after completing a set of sessions
Results Duration Over 1 year, upon completing a set of sessions
Cost Starts at 199€ (session price per package deal)
Technique Injectable, non-invasive treatment
Doctor’s Specialty Dermatologist, Plastic Surgeon
Pain level Painless
Anaesthesia Local anesthetic cream
Recovery Time Face redness for about 24 hours after treatment
Consultation Appointment Free of charge

The treatment – Results

  • Total Plasma Lift

  • Total Plasma Lift

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Top combo facial treatment!

The application of Fractional Laser offers smooth and luminous skin, without imperfections and discolorations, while the autologous PRP mesotherapy that completes the Total Plasma Lift treatment deeply hydrates and activates the natural tightening process.



Total Plasma Lift

What it it?

The Total Plasma Lift anti-aging protocol is a bloodless lift created by combining the two most effective deep regeneration treatments, Fractional Laser and PRP. The application is painless and the glow and lift effect begins to be seen immediately and becomes more and more impressive with each passing day.

This is a very effective, combo treatment for deep regeneration, hydration, tightening and smoothing of the skin on the face, neck and décolleté. It can also be applied to various areas of the body, in fact anywhere we want to correct skin problems such as scars, wrinkles, sagging and stretch marks. Finally, it has very good results on discolorations, freckles and melasma on the face or body.

Total Plasma Lift

How does it work?

The Total Plasma Lift anti-aging treatment consists of the combination of two top treatments, Fractional Laser CO2 and PRP.

In the first step of the treatment, Fractional Laser beams selectively scan the entire surface of the skin, acting on the deeper layers of the epidermis, resulting in the “awakening” of fibroblasts, the cells that produce collagen and elastin. Fractional Laser, making use of fractional technology, creates tiny holes in the skin surface allowing for better penetration of the active stem cells, which are injected into the epidermis with the PRP treatment that follows.

The second step, autologous PRP (Platelet Rich Plasma) stem cell mesotherapy, takes advantage of the regenerative and healing properties of blood plasma. PRP is applied injectably, or with Microneedling, to the face, even in the most sensitive areas such as the area around the eyes and mouth, and enhances the repair mechanism, tightening and production of new collagen, while fading fine wrinkles and acne scars more quickly for complete facial rejuvenation.

How Total Plasma Lift works.

Areas of application

Total Plasma Lift to the face.


The treatment can be applied all over the face, by “scanning” the skin in the first step of the Fractional Laser and injecting the valuable and deeply regenerative PRP plasma in the second step. The treatment provides almost immediate tightening and hydration and in the weeks to come you will see your skin more radiant, smooth and evenly toned.

Total Plasma Lift application on the eyes by Dr. Konstantina Mamali.

Eyes & Mouth

The Total Plasma Lift protocol that we apply at Cosmetic Derma Medicine includes a third step, the application of PRP with the Microneedling head, expanding the treatment areas on the sensitive skin around the eyes and mouth. Bags under the eyes are reduced while small lines and wrinkles around the eyes and upper lip are noticeably smoothed.

Total Plasma Lift application on the décolleté by the dermatologist.

Neck & Décolleté

The delicate and sensitive skin on the neck and décolleté is deeply moisturized and nourished. Fractional Laser treatment preceding PRP removes damaged skin surface cells and activates collagen and elastin production. This allows you to enjoy smoother and more elastic skin, with an even tone.


  • Combines the action of two treatments and maximizes the skin regeneration effect

  • Skin improvement continues for a long time after the treatment

  • Facial regeneration, tightening, hydration and smoothing of the skin

  • Smoothing of small wrinkles around the mouth and on the sides of the eyes

  • Safe, short and painless treatment in the dermatology clinic

  • Short recovery and return to everyday life

Total Plasma Lift

Step by step

1st Step

During your appointment you discuss with the dermatologist who evaluates your skin and suggests treatment areas. The doctor explains the treatment process and what to expect after the session.

Before starting the treatment, the practitioner proceeds with a simple blood draw and centrifuges the blood. When the centrifugation is complete, the plasma, a yellowish liquid that has a higher concentration of platelets compared to their normal presence in the blood, is collected.

Visit to the clinic for Total Plasma Lift.

2nd Step

In the meantime, the aesthetician carefully cleans your skin and asks you to remove any jewellery. Depending on the extent of the area to be treated, an anaesthetic cream may be applied topically. At this stage you need to wait 15-20 minutes for the cream to take effect.

Before starting the treatment, the aesthetician removes the anaesthetic cream and applies special eye protection glasses to protect the eyes in order to start the treatment.

The Total Plasma Lift treatment starts with the application of Fractional Laser.

3rd Step

The treatment starts with the application of the Fractional Laser. The doctor adjusts the special spot size of the laser in size and shape so that no part of the skin in the treatment areas is left uncovered, adjusts the energy, power and depth of action of the laser. Then, it scans the surface of the skin of the face or neck with the beam.

During application, we observe dots (so-called dots) forming on the skin surface from the laser action. This happens because the fractional laser energy beam is split into smaller beams and creates controlled injury at specific points, so that healing by the neighbouring healthy skin cells is accelerated.

4th Step

After the laser, the PRP phase follows. Using a very fine syringe, the doctor injects the plasma solution into the skin, covering the selected part of the face with several small “pinches”. These pricks form bumps on the surface of the skin, like small blisters, which disappear over the next few hours.

For an even more enhanced effect, in the Total Plasma Lift treatment an additional step follows: The scanning of the skin with the special Microneedling head that painlessly creates tiny “channels” on the surface of the epidermis to allow the plasma solution to penetrate the skin to the required depth.

The great advantage of the Microneedling head is that in the hands of an experienced dermatologist it can even be applied to the sensitive skin around the eyes and mouth.

Dr. Konstantina Mamali applies PRP and completes the Total Plasma Lift treatment.

5th Step

At the end of the treatment, the nurse cleans the skin at the application sites and will apply antibiotic ointment as a precautionary measure. This is followed by the application of a rich moisturizer and sunscreen for complete protection from the sun and then the doctor will give you advice on how to care for your skin in the days to come.

Adhering to them is very important to see the best possible results for your skin more quickly.

Antibiotic ointment, moisturizer and sunscreen are applied before the patient's departure.

Helpful information

Prior to the treatment


Bonus tips

  • Safe and effective

    Total Plasma Lift is a treatment of aesthetic dermatology that does not create any risk of side effects, as the substance injected into the skin, the plasma, comes from our own body. It is a non-invasive treatment, simple and painless, and the results are immediately visible from the first session.

  • Repetition is necessary

    To enjoy the best possible result, it is recommended to repeat the treatment within a month, while a total of 4-5 applications are required, depending on the age, the problem and the needs of each skin.

  • The ultimate beauty tip

    Good hydration of the body “nourishes” the skin and accelerates the healing process. Drink plenty of water and enrich your diet with seasonal fruits and vegetables that hydrate “from within”, increasing your intake of vitamins and minerals that are valuable for your skin.