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Mesotherapy with polynucleotides

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What is the treatment Polynucleotides

Polynucleotide mesotherapy has emerged in recent years as an innovative treatment for skin rejuvenation and regeneration, delivering remarkable results. This advanced technique involves the injection of polynucleotides into the dermis, the middle layer of the skin, where they act at the cellular level. Leveraging the properties of DNA, this cutting-edge treatment stimulates the skin’s natural repair mechanisms, boosts hydration, and enhances tissue elasticity.

In contrast to many traditional therapies, polynucleotide mesotherapy provides a natural solution for combating the signs of aging while significantly improving overall skin health.

Treatment Duration 20-30 minutes
Result Appears Right after treatment – Final results after completing a set of sessions
Results Duration Up to 12 months
Cost Starts at 450€ (session price per package deal)
Technique Injectable, non-invasive treatment
Doctor’s Specialty Dermatologist, Plastic Surgeon
Pain Level Painless
Anaesthesia Local anesthetic cream
Recovery Time Face redness for the first hours after treatment

The application of the treatment

  • Polynucleotides mesotherapy treatment

  • Polynucleotides mesotherapy treatment

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What are polynucleotides?

Polynucleotides, such as DNA and RNA, are biological macromolecules composed of chains of smaller units called nucleotides. Each nucleotide consists of a sugar molecule, a phosphate group, and a nitrogenous base, and serves as a building block of our genetic material.

In aesthetic medicine, we use injectable polynucleotides, which are typically derived from salmon or trout sperm. These polynucleotides have been specially processed in the laboratory to preserve their biological properties. This allows them to stimulate the skin’s ability to repair and regenerate itself.

How polynucleotides work

The action of polynucleotides is multifaceted, offering multiple benefits through a combination of hydration, collagen stimulation, and cell renewal.

Hydration: Polynucleotides have the extraordinary ability to retain huge amounts of water—up to 10,000 times their weight—far exceeding the hydrating power of hyaluronic acid. This unique property allows them to provide deep and long-lasting hydration to the skin, contributing to a smoother, more elastic, and youthful appearance.

Collagen & Elastin Stimulation: Polynucleotides activate fibroblasts, the cells responsible for producing collagen and elastin, two key proteins essential for skin firmness and elasticity. This stimulation leads to a gradual reconstruction of the skin’s structure, addressing wrinkles and sagging.

Antioxidant Action: Polynucleotides also act as antioxidants, neutralizing free radicals caused by solar radiation and other environmental factors that contribute to aging.

Cellular Renewal: By protecting against oxidative stress and promoting cellular repair, polynucleotides accelerate the skin’s healing processes. This results in a reduction of signs of aging, such as fine lines, wrinkles, scars, and marks.

 

Improving Skin Tone: In addition, they soothe inflammation and restore the balance of melanocyte activity (skin pigmentation), resulting in a more even and refreshed skin tone without adding the volume associated with products like fillers.

Glow Enhancement: Improved microcirculation and skin hydration lead to a brighter and more radiant complexion.

Even Tone & Radiance: Polynucleotides help regulate skin pigmentation, soothe inflammation, and improve microcirculation. This results in a more even tone and a natural glow, without adding volume like facial fillers.

Natural & Long-Lasting Results: Polynucleotide mesotherapy offers natural and long-lasting results, enhancing the appearance of the skin without altering facial features.

Results and duration

The effects of polynucleotide mesotherapy are gradual and long-lasting, offering a natural and rejuvenating solution for your skin.

  • Immediate Results: Right after the treatment, you may notice an immediate improvement in skin hydration and firmness.
  • Short-term Results: Within 2-4 weeks, most patients observe an enhancement in skin texture and a reduction in fine lines.
  • Long-term Results: The full benefits of the treatment become evident after 2-3 months, as collagen and elastin production gradually increases.
  • Duration: Results typically last 6-12 months, though this can vary depending on skin type, age, and lifestyle.
  • Maintenance Treatments: To maintain the results, maintenance treatments are recommended every 6-12 months.

Mesotherapy Procedure with Polynucleotides

Mesotherapy with polynucleotides is a minimally invasive procedure carried out in clinics and medical offices by specialized physicians. The process involves the following steps.

Step 1: Initial session and assessment

Before the treatment, a detailed consultation with the doctor is conducted. During this session, the skin type, patient concerns, and treatment goals are assessed. The physician explains the procedure, the expected outcomes, and any precautions.

Step 2: Preparation

This is a necessary step before the treatment is administered. The skin is carefully cleansed and disinfected. If needed, a topical anesthetic cream is applied to minimize any discomfort.

Step 3: Application

When administering the treatment, the doctor injects the polynucleotides into the skin using microneedling. In sensitive areas, such as around the eyes, a blunt cannula is often used to minimize the risk of bruising. The procedure typically takes 15-30 minutes, depending on the area being treated.

After the treatment

After the procedure is complete, the area can be gently cleaned, and a soothing product applied. The physician will provide detailed instructions for post-treatment care

Comparison with other treatments

Polynucleotides offer unique advantages compared to other popular aesthetic treatments.

Combination with other treatments

Polynucleotide mesotherapy can be effectively combined with other treatments, providing personalized solutions tailored to each individual’s needs and goals.

With Hyaluronic Acid: The combination provides the immediate hydration and volume of hyaluronic acid, while polynucleotides work deeply to stimulate collagen and elastin production for long-lasting results.

With Radiofrequency (RF) or Fractional Laser: Combining polynucleotide mesotherapy with RF or Fractional Laser significantly enhances skin elasticity, reduces the appearance of wrinkles, and offers tightening

With microneedling: Microneedling creates micro-injuries in the skin, enhancing the penetration of polynucleotides and stimulating collagen production for even more impressive results.

With PRP (Platelet-Rich Plasma): The combination of polynucleotide mesotherapy and PRP, rich in growth factors, offers excellent results in skin rejuvenation, hair loss treatment, and scar healing.

Side effects of polynucleotides

Polynucleotide treatments are generally safe when administered by qualified physicians and using certified products.

Side effects are typically minimal and temporary. Mild irritation, redness, swelling, and minor bruising may occur but usually resolve within one to two days. More serious complications, such as allergic reactions or infections, are extremely rare.

The treatment is not recommended for pregnant or breastfeeding women, individuals with autoimmune diseases, those with active infections, or anyone with allergies to the product’s ingredients.

Why Choose Us for Polynucleotide Mesotherapy?

At Cosmetic Derma Medicine, we provide the highest level of care. Our experienced physicians specialize in administering polynucleotide treatments, ensuring optimal results tailored to your skin’s unique needs. We use only the highest quality products and the latest techniques to help you achieve the best possible outcomes.

If you are considering a polynucleotide treatment or have any questions, please leave us a message, and we will get back to you as soon as possible. Alternatively, you can call us to schedule your appointment.

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